核心问题
（1）There have been major changes in advertising in the past sixty years.
(2) There has been little change in the patient's condition...
change 到底是可数名词,还是不可数名词?
词典解答
change 一般用作可数名词。但有时也用作不可数名词。请分析下面的实例：
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There has been a change in the programme. 节目有变动。
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After two hot summers, people were talking about a change in the climate. 在两个炎热的夏季之后，人们便谈论起气候的变化。
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Tell your partner about the changes to your plan because of your illness. 把你因病改变计划的事儿告诉你的伙伴。
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He lived through a time of great social change. 他是从社会发生重大变革的时期生活过来的。
[注意]作“找回的零钱”解的 change 是个不可数名词：
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There isn't any trouble. I'm just waiting for my change. 没事儿。我只是等着找钱。
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I handed over a pound and got 38 pence change. 我递过去1英镑，找给我38便士。